Development of Novel Antibody-Based Approach for T1D

Document Type : Abstracts

Abstract

Type 1 diabetes (T1D) is one of the most common chronic diseases of childhood. It is prompted by the autoimmune destruction of insulin-producing beta cells in pancreatic islets and leaves affected individuals dependent on daily insulin injections. At present T1D treatment is done by lifelong delivery of novel kinds of insulin which have been synthesized 
recently. Numerous approaches have attempted to prevent or stop islet cell destruction on the basis of immunotherapies to block T cell responses against β cells antigens which are quite common at the time of initiation as well as development of T1D.