The Evolving Role of Long Noncoding RNA HIF1A-AS2 In Diabetic Retinopathy: A Cross-Link Axis Between Hypoxia, Oxidative Stress and Angiogenesis Via MAPK/VEGF Dependent Pathway

Document Type : Abstracts

Abstract

Diabetic retinopathy (DR) signifies a frequent serious diabetic complication influencing retinal structure and function. Dysregulation of lncRNAs drives a wide array of human diseases especially diabetes; thus, we aimed to study lncRNA HIF1A-AS2 role and its interplay with hypoxia, oxidative stress (OS), and angiogenesis in DR.