Autoimmune aspect of type 2 diabetes: Diagnostic and therapeutic perspective

Document Type : Review Article

Abstract

Type 2 diabetes (T2D) is a multifactorial and multilayer disease, characterized by an altered metabolism of glucose, fat, and proteins. Hyperglycemia is the main common feature defining T2D, and clusters of patients are identifiable according to the specific combination of insulin resistance (IR) and absolute or relative insulin deficiency.